The ACTA team

Leadership to translate decades of Alzheimer’s discoveries into new therapies

Acta joins Alzheimer’s research pioneers, commercial leaders, clinical development experts, and biotech executives with deep experience moving discoveries to patients.

Scientific team in lab coats reviewing research together

Deep expertise. Shared purpose. Seasoned leadership.

Experienced leaders across science, clinical development and commercialization.

Portrait of Rudolph E. Tanzi

Rudolph E. Tanzi, PhD

Scientific founder & director

Harvard Medical School-Massachusetts General Hospital neuroscientist, co-discoverer of all three familial early-onset Alzheimer’s genes, and co-creator of Alzheimer’s-in-a-Dish™ .

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Portrait of George Alex

George Alex

Co-founder, CEO & director

Seasoned C-level executive and former investment banker with 40+ years of company-building experience and nearly $40B in capital formation and M&A transactions.

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Portrait of Yuan-Di Halvorsen

Yuan-Di Halvorsen, PhD

Chief operating officer

Clinical and regulatory leader with nearly 30 years advancing therapies from discovery through late-stage development, regulatory submission, manufacturing, and quality systems.

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Portrait of Kevin Rynearson

Kevin D. Rynearson, PhD

Chief scientific officer

GSM biology and rational drug design expert who advanced Acta’s lead GSM‑669T candidate from rational design through IND-enabling studies.

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Portrait of Gene Williams

Gene Williams

SVP of strategy

Biotech and health-tech executive with 40+ years in company formation, product development, commercialization, capital formation, and strategic transactions.

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Portrait of Angela Britton

Angela Britton

Vice president clinical operations

Clinical operations leader with 25+ years delivering early-phase trials across pharma, biotech, government, and academia, with focus in neurology and special populations.

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Scientific advisors

World-class advisors across Alzheimer’s disease research, biomarkers, and treatment

Portrait of David M. Holtzman

David M. Holtzman, MD

AdvisorMorris Distinguished ProfessorDept. of NeurologyWashington University School of Medicine

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Portrait of William Mobley

William Mobley, MD, PhD

AdvisorDistinguished Professor of NeurosciencesUC San Diego School of Medicine

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Portrait of Sangram S. Sisodia

Sangram S. Sisodia, PhD

AdvisorReynolds Family Professor of Neuroscience University of Chicago

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